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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences Lomefloxacin hydrochloride | 98079-52-8 | MFCD00214312 | 10G
Lomefloxacin hydrochloride | Mol Wt: 387.81 | 98079-52-8 | MFCD00214312 | 10G
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5000883584 4-CHLOROPYRIDINE-2-CARBO 100G
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5000884000 8-BROMO-2-METHYLQUINOLIN 5G
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Selleck Chemical LLC JNK-IN-8 S4901-25mg
JNK-IN-8 (JNK Inhibitor XVI) is the first irreversible JNK inhibitor for JNK1 JNK2 and JNK3 with IC50 of 4 7 nM 18 7 nM and 1 nM 10-fold selectivity against MNK2 Fms and no inhibition to c-Kit Met PDGFR in A375 cell line
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5000883964 7-BROMOQUINOLINE 25G
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5000882987 13-BENZOTHIAZOLE-2-CARBA 5G
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5000883287 HYDROQUININE 10G
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5000883424 S-55667788-OCTAHYDRO-11- 25G
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5000847021 R -CHROMAN-4-AMINE HYDR 1G
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Medchemexpress LLC Nilotinib | 641571-10-0 | 99.9% | 529.52 | 200 MG
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Nilotinib is an orally available Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity, designed for research use. It exhibits significant inhibitory effects against Bcr-Abl and various other targets, making it suitable for studies on cell proliferation and cytotoxicity.
- Exhibits antiproliferative activity in A549 cells with an IC50 of 6.63 μM.
- Shows antiproliferative activity in BJ cells with an IC50 of 12.8 μM.
- Inhibits various BCR/ABL p210 mutants (GI50 0.004 μM to > 10 μM).
- Induces cytotoxicity against various BaF3 cell lines.
- Used in CCK-8 assays for IC50 assessment in liver cancer cell lines.
- Useful for observing anti-colony formation effects.
- Utilized for immunohistochemistry of primary tumors.
- Investigated for its direct effect on cytotoxic lymphocytes.
- Applied for cell cycle analysis.
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Medchemexpress LLC Deucravacitinib | 1609392-27-9 | 99.9% | 425.46 | 200 MG
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Deucravacitinib is a highly selective, orally bioavailable allosteric TYK2 inhibitor designed for the treatment of autoimmune diseases. It works by selectively binding to the TYK2 pseudokinase (JH2) domain, which blocks receptor-mediated Tyk2 activation by stabilizing its regulatory JH2 domain. This action inhibits IL-12/23 and type I IFN pathways. It is used for studying moderate to severe plaque psoriasis.
- Highly selective, orally bioavailable allosteric TYK2 inhibitor
- Designed for the treatment of autoimmune diseases
- Selectively binds to the TYK2 pseudokinase (JH2) domain
- Blocks receptor-mediated Tyk2 activation
- Inhibits IL-12/23 and type I IFN pathways
- Used for studying moderate to severe plaque psoriasis
- FDA's first de novo deuterium
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Sigma Aldrich Fine Chemicals Biosciences Quinine suitable for fluorescence, anhydrous, >=98.0% (dried material, NT) | 130-95-0 | MFCD00198096 | 5G
Quinine suitable for fluorescence, anhydrous, >=98.0% (dried material, NT) | Purity: >=98.0% (dried material, NT) | Mol Wt: 324.42 | 130-95-0 | MFCD00198096 | 5G
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Sigma Aldrich Fine Chemicals Biosciences Mefloquine hydrochloride >=98% (HPLC), powder | 51773-92-3 | MFCD00797519 | 100MG
Mefloquine hydrochloride >=98% (HPLC), powder | Purity: >=98% (HPLC) | Mol Wt: 414.77 | 51773-92-3 | MFCD00797519 | 100MG
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5000884225 65H-PHENANTHRIDINONE 25G
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eMolecules 1078-30-4 | 7-Quinolinecarboxylic acid | Ambeed | MFCD00047617 | 173.171 | C10H7NO2 | 98.000 | OC(=O)c1ccc2cccnc2c1 | 100mg | 525018153
7-Quinolinecarboxylic acid | Ambeed | 1078-30-4 | MFCD00047617 | 173.171 | C10H7NO2 | 98.000 | OC(=O)c1ccc2cccnc2c1 | 100mg | 525018153
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